What are the risks during and after placement of a PICC?

• There may be slight discomfort during the procedure.

• Bleeding may occur at the insertion site.

• It is sometimes necessary to attempt more than once and it may not be possible to insert the entire length of the PICC.

• During insertion of a PICC, accidental puncture of an artery, nerve, or tendon can occur near the insertion site. However, this is a rare event.

• A clot may form around the catheter in the vein (thrombosis), which can cause swelling and pain in the arm.

• Inflammation in a vein (phlebitis) can develop from the use of all types of IVs, including PICCs.

• An infection may occur at the insertion site or in the bloodstream.

• The PICC can come out, partially or completely, if not well-secured and completely covered.

• The PICC can move out of position in the vein and may need to be removed or repositioned.

• The PICC may become blocked. Medication may need to be used to clear it.